• Antimicrobial peptides in Urticina eques and Echinus esculentus. Isolation, characterisation, and structure-activity relationship studies 

      Solstad, Runar Gjerp (Doctoral thesis; Doktorgradsavhandling, 2016-12-09)
      Bacterial resistance to antibiotics has become a serious global problem. Infections that once were easily cured with antibiotics have now become nearly impossible to treat. Thus, there is a desperate need for new antibacterial drugs. Antimicrobial peptides (AMPs) are a diverse group of compounds. Amongst their unique features are their ability to kill bacteria (often both Gram-positive and Gram-negative) ...
    • First observation of seasonal variations in the meat and co-products of the snow crab (Chionoecetes opilio) in the Barents Sea 

      Solstad, Runar Gjerp; Descomps, Alexandre; Siikavuopio, Sten Ivar; Karstad, Rasmus Tørnes; Vang, Birthe; Whitaker, Ragnhild Dragøy (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-24)
      The snow crab (<i>Chionoecetes opilio</i>), SC, is a newly established species in the Barents Sea. The snow crab fishery has established itself as a new and profitable industry in Norway in the last decade. The fishery started as a year-round fishery, without any information of possible seasonal variations in the quality of the product. In 2017 a total allowable catch was established by the Norwegian ...
    • New Disulfide-Stabilized Fold Provides Sea Anemone Peptide to Exhibit Both Antimicrobial and TRPA1 Potentiating Properties 

      Logashina, Yulia A.; Solstad, Runar Gjerp; Mineev, Konstantin S.; Korolkova, Yuliya V.; Mosharova, Irina V.; Dyachenko, Igor A.; Palikov, Victor A.; Palikova, Yulia A.; Murashev, Arkadii N.; Arseniev, Alexander S.; Kozlov, Sergey A.; Stensvåg, Klara; Haug, Tor; Andreev, Yaroslav A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-29)
      A novel bioactive peptide named τ-AnmTx Ueq 12-1 (short name Ueq 12-1) was isolated and characterized from the sea anemone Urticina eques. Ueq 12-1 is unique among the variety of known sea anemone peptides in terms of its primary and spatial structure. It consists of 45 amino acids including 10 cysteine residues with an unusual distribution and represents a new group of sea anemone peptides. The 3D ...
    • Novel antimicrobial peptides EeCentrocins 1, 2 and EeStrongylocin 2 from the Edible sea urchin Echinus esculentus have 6-br-trp post-translational modifications 

      Solstad, Runar Gjerp; Li, Chun; Isaksson, Johan; Johansen, Jostein a; Svenson, Johan; Stensvåg, Klara; Haug, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-23)
      The global problem of microbial resistance to antibiotics has resulted in an urgent need to develop new antimicrobial agents. Natural antimicrobial peptides are considered promising candidates for drug development. Echinoderms, which rely on innate immunity factors in the defence against harmful microorganisms, are sources of novel antimicrobial peptides. This study aimed to isolate and characterise ...